Latest · Guide
How to Check Your Genome Download Isn't Corrupted
Genome files can break silently in transit. How to verify BAM, CRAM, FASTQ and VCF downloads with MD5 or SHA-256 checksums on Mac, Windows and Linux.
Genome files can break silently in transit. How to verify BAM, CRAM, FASTQ and VCF downloads with MD5 or SHA-256 checksums on Mac, Windows and Linux.
How to read a VCF header: fileformat, reference, contig, INFO, FORMAT and FILTER lines, the #CHROM sample column, and how to tell GRCh37 from GRCh38.
Low-pass sequencing reads a fraction of your genome and imputes the rest; 30x reads it directly. What each can find, who each suits, and how to tell them apart.
Imputation fills gaps in array DNA data using reference panels. Why its accuracy varies by ancestry and rarity, and why imputed calls aren't medical results.
Protect raw genome files with FileVault, BitLocker, LUKS, VeraCrypt, gpg or age: what each protects, when you need a terminal, and how not to lose access.
Thinking of sharing your DNA with research? Learn how broad consent, de-identification, withdrawal and Certificates of Confidentiality work, and what to ask.
How DNA data moves in a sale or bankruptcy, using 23andMe's 2025 Chapter 11 and sale to TTAM as the case study, plus the steps you can take to protect yours.
Where to find the clauses that control your DNA: sample storage, deletion exceptions, research consent, sharing, police requests, mergers and breaches.
BAM and CRAM both store your aligned genome reads, but CRAM needs the exact reference FASTA to be read. When to convert, the samtools commands, and checks.
A worrying consumer DNA or raw-data finding needs clinical confirmation. Here is who orders the retest, what to bring, and what a negative result means.
Whole-genome raw files can run to a few hundred gigabytes. Here's what you're storing, a 3-2-1 backup plan, encryption, and how to check copies aren't corrupted.
Once you have your VCF, the ecosystem opens up. These twelve free or freemium tools let you generate more reports, ancestry analyses, disease risk models, and family comparisons from the…
A historical look at Dante Labs sale timing, annotated with current October 2026 pricing so old promotional prices are not mistaken for live offers.
Thinking of gifting whole genome sequencing? Who it suits, who it doesn't, a five-minute privacy check, timing, and current Dante pricing checked Oct 25, 2026.
Historical sub-$200 WGS sales, what current pricing looks like, and how to verify a future promotion without relying on an old coupon or sale price.
UK WGS buying guide covering current-price verification, VAT, delivery, raw-data access and practical turnaround considerations.
If you and your partner both carry a recessive variant, your child has a 25% chance of the condition. WGS carrier screening covers hundreds of these genes. Here's what to test, when, and…
How to evaluate current WGS promotions, bundles, raw-data access and checkout discounts without assuming historical flash-sale prices will return.